Not all collagen is considered equal. Supplementation sources can vary from porcine, bovine or marine — all variations in quality and molecular weight can affect absorption and efficacy.
Collagen is broken down in the digestive tract, whereafter it enters the bloodstream and accumulates in various tissues depending on it's molecular weight. For superior absorption, a collagen supplement with low molecular weight is key.
Collagen is the most abundant protein in the human body, making it the most prevalent structural material in the human body after water. This is important when we understand that collagen is a necessary component for building beautiful skin. As much as 75% of the extracellular matrix is comprised of collagen.
In a recent research review the efficacy of collagen supplementation was tested for dermatological applications. The researchers looked at 8 studies using collagen hydrolysate (which has a low molecular weight) at doses ranging from 2.5-10 grams per day for a period of 6-24 weeks. These studies found a reduction of wrinkle volume, improved skin elasticity, increased skin moisture and a significant reduction in the degree of cellulite.
Additionally, The use of collagen has also expanded into treating such dermatological conditions as atopic and allergic contact dermatitis. The aforementioned review also looked at one 12-week study that sought to examine the effect of collagen supplementation with atopic dermatitis with a dose of 3.9 grams a day. Those who supplemented with collagen saw a significant decrease in immune response and inflammation after 12 weeks. Severity of skin eruption areas, skin hydration and itchiness were all reduced with collagen supplementation.
Collagen is effective in supporting various dermatological conditions such as wound healing, skin elasticity, and suppleness. Other applications for collagen supplementation include osteoarthritis, osteoporosis, improving blood pressure and insulin resistance. As with all things, quality is important. It is necessary to use a high-quality collagen supplement that is supported by clinical research and is of a low molecular weight in order to optimize absorption and intended results.
Source: Choi FD, Sung CT, et al. Oral Collagen Supplementation: A Systemic Review of Dermatological Applications. J Drugs Dermatol. 2019 Jan 1;18(1):9-16.