Additional Notes on CBD:
While THC, the psychoactive chemical found in cannabis, is a restricted substance that is not legal in several states and countries, the compound cannabidiol is: Mary Barna Bridgeman and Daniel T. Abazia, “Medicinal Cannabis: History, Pharmacology, And Implications for the Acute Care Setting,” Physical Therapy 42, no. 3 (March 2017): 180–188, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312634/
CBD is a cannabinoid that composes up to 40 percent of the marijuana plant: Alline Cristina Campos et al., “Multiple Mechanisms Involved in the Large-Spectrum Therapeutic Potential of Cannabidiol in Psychiatric Disorders,” Philosophical Transactions of the Royal Society B: Biological Sciences 367, no. 1607 (December 2012): 3364–3378, https://doi.org/10.1098/rstb.2011.0389
CBD acts as an antagonist of THC by turning off or turning down anything that would activate the receptors through which THC exerts its effects. CBD itself does not, like THC, attach to receptors associated with addiction, so it is neither addictive or habit-forming: Shenglong Zou and Ujendra Kumar, “Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System,” International Journal of Molecular Sciences 19, no. 3 (March 2018): 833, https://doi.org/10.3390/ijms19030833; Expert Committee on Drug Dependence, “Cannabidiol (CBD) Critical Review Report,” World Health Organization, June 2018, https://www.who.int/medicines/access/controlled-substances/CannabidiolCriticalReview.pdf
CBD also has no psychoactive effects, and there is a growing body of research to support CBD use for recovery: Bridgeman and Abazia, “Medicinal Cannabis: History,” 180–188, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5312634/
CBD is particularly potent against inflammation, which is one of the leading contributors to conditions like heart disease, cancer, chronic lower respiratory disease, stroke, Alzheimer’s, diabetes, and nephritis: Natalya M. Kogan and Raphael Mechoulam, “Cannabinoids in Health and Disease,” Dialogues in Clinical Neuroscience 9, no. 4 (December 2007): 413–430, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202504/; Martin Frisher et al., “The Role of Cannabis and Cannabinoids in Diabetes,” The British Journal of Diabetes & Vascular Disease 10, no. 6 (2010): 267–273, https://doi.org/10.1177/1474651410385860; Claudia Ho, Dan Martinusen, and Clifford Lo, “A Review of Cannabis in Chronic Kidney Disease Symptom Management,” Canadian Journal of Kidney Health and Disease 6 (2019): 2054358119828391, https://doi.org/10.1177/2054358119828391
CBD is also effective against acute inflammation, which you might encounter, say, after a long day of racing or working out… CBD can also reduce levels of the inflammatory compound interleukin-6: Prakash Nagarkatti et al., “Cannabinoids as Novel Anti-Inflammatory Drugs,” Future Medicinal Chemistry 1, no. 7 (October 2009): 1333–1349, https://doi.org/10.4155/fmc.09.93
The problem with CBD is that it is not naturally highly bioavailable because CBD oils, capsules, and powders are not water soluble. Considering that your body is over 60 percent water, you have to find a way to overcome this problem to enjoy the benefits of this cannabinoid: Natascia Bruni et al., “Cannabinoid Delivery Systems for Pain and Inflammation Treatment,” Molecules 23, no. 10 (October 2018): 2478, https://doi.org/10.3390/molecules23102478
Turmeric plays a significant role here because the isolated curcuminoids (which are the active ingredients of a high-curcumin-containing turmeric plant) mix with the cannabinoids and terpenoids of CBD, causing their bioavailability to explode: Bruni et al., “Cannabinoid Delivery Systems,” 2478, https://doi.org/10.3390/molecules23102478
When you take CBD with curcumin or turmeric high in curcumin, you can get five to ten times the effects: Grant Hosking, “The Synergistic Effects of Turmeric and CBD,” Modern Nature, February 12, 2019, https://modernnature.com/blogs/articles/the-synergistic-effects-of-turmeric-and-cbd; Kelly Harrington, “Combining Hemp Extract and Curcumin,” Healthy Goods, April 12, 2019, https://healthygoods.com/blog/combining-hemp-extract-and-curcumin/
CBD topical lotions can be just as effective as or more effective than oral CBD supplementation for spot-targeting joints: D.C. Hammell et al., “Transdermal Cannabidiol Reduces Inflammation and Pain-Related Behaviours in a Rat Model of Arthritis,” European Journal of Pain 20, no. 6 (July 2016): 936–948, https://doi.org/10.1002/ejp.818
recommend just 10 to 20 mg of CBD if you have never used it before: Kerstin Iffland and Franjo Grotenhermen, “An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies,” Cannabis and Cannabinoid Research 2, no. 1 (2017): 139–154, https://doi.org/10.1089/can.2016.0034